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New Ways to Make Measurements in the Life Sciences. |
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Technical Information Molday ION™ is an iron oxide-based super paramagnetic (USPIO) contrast reagent having a colloidal size of 30 nm. This reagent is classified as a darkening agent acting through the T2 relaxation process. As an intravascular contrast agent, Molday ION has a blood half-life of several hours and can be used in a wide range of cardiovascular and vascular research. In addition, we also offer Molday ION (-) that has a negative charge colloidal surface and is formulated for labeling cells using Poly-L-Lysine. Molday ION C6Amine, as its name implies, is engineered to have terminal amino groups with different length spacers. They are designed for cell labeling and to allow for efficient labeling with ligands, peptides, proteins, and nucleic acids (RNAi, DNA, etc.). As a result, new biological properties can be conferred to the reagent, such as targeting to a specific receptor site. These reagents are also classified as a darkening agent acting through the T2 relaxation process. Molday ION Carboxyl Terminated nano-magnetite is specifically designed for conjugating your ligand, peptide, antibody, and protein using water soluble carbadiimide. This T2 MRI contrast agent has a concentration of 2.5 mg Fe/ml, a size of ~30 nm, and a zeta potential of about -35 mV. The nanoparticle is designed so that it is not bound to or internalized by cells allowing cell labeling exclusively from your conjugated ligand. This product is well suited for cell targeting experiments! Molday ION Rhodamine B™ is an iron oxide-based super paramagnetic contrast reagent having a colloidal size of 35 nm. The colloidal particle is cross-linked and labeled with rhodamine B, which is a fluorescent dye. As a result, this reagent can be visualized by both MRI and by fluorescence. For MRI, this reagent is classified as a darkening agent acting through the T2 relaxation process. For fluorescence, the rhodamine B label excitation wavelength is 555 nm and the emission is at 565-620 nm. The reagent ideal for many cell labeling and tracking applications. Download a PDF picture of labeled cells! The Product Pricing Molday
ION,
Molday
ION Amine,
Molday
ION Carboxyl Terminated, and
Molday
ION
Rhodamine B, are
both packaged in 2 ml sealed
serum bottles. Additional
Molday
ION products
are listed on our price list. NOT FOR HUMAN USE.
Applications and Functionalities
Physical properties
Volume, Concentration and Price
Helpful Download Files Application Notes: Cell labeling and tracking by MRI is a growing area of interest. BioPAL
provides a general method to label and fix cells using Molday
ION product
line. BioPAL provides a method to label poly-l-lysine on to
Molday
ION (-) for cell labeling. BioPAL provides
a method to stain cells with Prussian Blue to visualize the presence of iron.
References 1. J Clin Invest 2008 118(5):1965-1973.
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