Technical Information
FIT-RPFTM kits provide a
superior analytical method to measure effective renal plasma flow.
BioPAL's FIT-RPF test, whose analytical segment uses immunoassay, overcomes all
the major limitations associated with current analytical technology. The
presence of a GFR marker, such as Gd-DTPA or Gd-DOTA, in the sample will not
affect the accuracy of the FIT-RPF measurement. Therefore, researchers can
simultaneously obtain a GFR and RPF measurement in the same subject using FITTM
kits.
Glomerular filtration rate (GFR) is the
measure of the total volume of plasma actually filtered through the glomerulus
per unit of time, while the effective renal plasma flow (RPF) is the measure of
the total volume of plasma passing through the kidney per unit time. These
two measurements can be obtained simultaneously using FIT and allows researchers
the ability to calculate the renal filtration fraction (FF). The FF is the
ratio of the GFR and EPF and represents the amount of plasma flowing through the
kidney that is actually being filtered. These are three fundamental
measurements in the field of nephrology.
The Product
FIT-RPF Kit (Patents Pending)
Coming Soon!
BioPAL offers a FIT-RPF kit that
supports iodohippurate as the renal flow marker.
- FIT-RPF Kit for Iodohippurate
BioPAL's FIT-RPF kit contains iodohippurate concentrate, rabbit iodohippurate antiserum,
HRP-iodohippurate-DTPA conjugate, HRP substrate and stop reagents, a goat anti-rabbit IgG coated
96 well plate, a plate sealer, iodohippurate kit manual and documentation.
Download a PDF price list.
Download a PDF kit manual.
Download a PDF MSDS.
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