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New Ways to Make Measurements in the Life Sciences. |
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Cell Labeling and Tracking The twenty-first century began with the completion of the human genome project and the dawn of proteomics and systems-biology. These emerging fields will attempt to understand how newly discovered proteins impact human physiology and disease. As researchers progress from molecular- and cellular-based studies to in vivo systems, innovative technologies are needed to allow multiple tracking of probes and multiple measurements of functional parameters in in vivo models. One arena of research that has emerged due to recent discoveries is the field of cellular transplantation. BioPAL has developed CELLTrack™ to aid researchers locate, track, and quantify implanted cells in in vivo systems. We currently offer seven different colloidal markers, with additional markers under development. Cellular uptake is via a variety of mechanisms following the incubation of cells with CELLTrack. Independent researchers have reported successful application of this product using a variety of different cell lines. We can also provide targeted material directed to specific receptors to maximize cellular uptake for specific cell lines on a custom basis. Several of the lanthanide labels can also be measured by time-resolved fluorescent technology and by magnetic resonance imaging (MRI). Therefore, researchers can take advantage of one, two or all three technologies to maximize data output. As a expansion on this theme, BioPAL offers CELLTrack that is co-labeled with rhodamine or fluorescein to provide researchers the ability to visualize cells by conventional fluorescent techniques. Development of this product line has, in part, been supported by a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant sponsored. See What's New! The Advantages Non-radioactive: All of BioPAL's products are stable and non-radioactive. As a result, this product is not a radiological toxin to the cells being labeled and the user will not require special licensing to use these products. Customer Reference list Download a recent poster presentation that was presented at the 2007 European Society of Cardiology Congress in Vienna, Austria by MG Biotherapeutic, which is a joint venture between Medtronic and Genzyme. In addition, we have compiled a brief list of references from researchers that have used and cited BioPAL products. Here's the link to the PDF file. If you would like to include your published research in our reference list, please contact us. The Product
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