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BioPAL, Inc.
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New Ways to Make Measurements in the Life Sciences.

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Cell Labeling and Tracking

The twenty-first century began with the completion of the human genome project and the dawn of proteomics and systems-biology.  These emerging fields will attempt to understand how newly discovered proteins impact human physiology and disease.  As researchers progress from molecular- and cellular-based studies to in vivo systems, innovative technologies are needed to allow multiple tracking of probes and multiple measurements of functional parameters in in vivo models.  One arena of research that has emerged due to recent discoveries is the field of cellular transplantation.

BioPAL has developed a number of innovative products to aid researchers locate, track, and quantify implanted cells in in vivo systems.  Many of these products can be found nowhere else!

To be directed to products designed for MRI applications, click one of the following:
1.  Iron-Based Products
     Iron-based products include, USPIOs, fluorescent USPIOs, and functional USPIOs.
     Specific products of interest: Molday ION Rhodamine B™ and Molday ION C6Amine
2.  Gadolinium-Based Products

Download posters that were presented at the Circulating Tumor Cells conference on the NIH campus - September 2009.  These posters discuss the use of iron-based USPIOs.
Download Poster Number 1
Download Poster Number 2

To be directed to products designed for neutron activation applications, click one of the following:
1.  Neutron Activation-Based Products

 

Cell Labeling and Cell Tracking Service
BioPAL and SBH Sciences provide a cell-labeling and cell-tracking service for those customers that do not have in-house cell-labeling capability.  Cells are labeled with colloidal probes developed at BioPAL, as listed above.  Colloidal probes can be detected by fluorescence, MRI and neutron activation.  Cells are grown, labeled and prepared for shipping at SBH Sciences.  The Client provides cells for labeling.  Following labeling, frozen cells are returned to the Client.  Applications include: CTC assays, immune-cell migration, inflammation studies, microbial and viral disease localization, and stem cell mediated tissue regeneration.

For more information, contact Dennis Vaccaro at BioPAL (508-770-1190) or Raphael Nir at SBH Sciences (508-650-6218, ext 214)  SBH Sciences web-site is www.sbhsciences.com.

 

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